Another revealing “experiment of nature” is Androgen Insensitivity Syndrome. In this case, there is a normal amount of testosterone circulating in a XY chromosome foetus, but each cell of its body is unable to react to it. This is similar to Turner’s Syndrome in that neither the mullerian or wolffian ducts (see above) mature and the external genitalia develops into an approximation of normal female genitals, but differs in that TDF stimulates the gonads into becoming functioning testicles in a XY chromosome body. The child is raised as a girl and is seen as a normal female until she fails to menstruate because she has no uterus. If her testes produce enough oestrogen (excess testosterone is converted into estrogen), she develops into a completely normal appearing (but lacking a uterus and upper vagina), sterile female with XY chromosomes and internal testicles.

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